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C1613
Sigma
Carbenicillin
Ready Made Solution, 100 mg/mL in ethanol/water, 0.2 μm filtered
| Synonym: | α-Carboxybenzylpenicillin solution |
| Linear Formula: | C17H18N2O6S |
| Molecular Weight: | 378.40 |
| MDL number: | MFCD00242604 |
| PubChem Substance ID: | 24892425 |
Description
| Biochem/physiol Actions | The antibiotic carbenicillin, an ampicillin analog, is a commonly used selection agent that binds and inhibits enzymes involved in the synthesis of the bacterial cell wall. It is active against most isolates of Pseudomonas aerogenosa and certain indole-positive Proteus strains that are resistant to ampicillin. The gene conferring resistance to ampicillin and its analogs, ampr, codes for the enzyme β-lactamase. Carbenicillin is less sensitive to β-lactamase than ampicillin. In addition it has a superior stability at low pH. Experiments have shown that the use of carbenicillin in place of ampicillin helps prevent overgrowth of satellite colonies. Effective concentration: 50 to 100 μg/ml. |
Properties
| sterility | 0.2 μm filtered |
| concentration | 100 mg/mL in ethanol/water |
| shipped in | wet ice |
| storage temp. | −20°C |
